Figure 4

Baseline double oblique coronal MR image acquired using a fat suppressed SPGR sequence with a 1.5 mm slice thickness and 0.31 mm × 0.31 mm in plane resolution. The area of the cartilage surface (AC) and the total subchondral bone area (tAB) are manually segmented in the medial tibia (MT) and weight-bearing medial femur (cMF). The part of the tAB covered by AC is defined as the cartilaginous area of bone (cAB), that not covered by the AC as the denuded area of bone (dAB).