Table 4 Serious adverse events occurring in patients switching between TNF antagonists
1st TNF antagonist (n = 417) | 2nd TNF antagonist (n = 83) | 3rd TNF antagonist (n = 18) | |
|---|---|---|---|
Upper respiratory infections | 8 | 1 | |
Urticaria | 3 | ||
Systemic lupus erythematosus | 2 | ||
Herpes zoster | 2 | ||
Rash | 3 | 1 | 1 |
Tuberculosis | 2 | 1 | |
Infusion reactions | 16 | 1 | |
Cardiac insufficiency | 3 | ||
Acute pancreatitis | 2 | ||
Cutaneous vasculitis | 2 | ||
Erythema | 3 | ||
Infectious arthritis | 2 | ||
Leukopenia | 1 |