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Table 3 Microarchitectural indices of lumbar vertebra

From: The combination therapy with alfacalcidol and risedronate improves the mechanical property in lumbar spine by affecting the material properties in an ovariectomized rat model of osteoporosis

Group

(/mm)

BV/TV (%)

BS/BV (%)

Tb.Sp (μm)

Tb.Th (μm)

Tb.N

Sham

0.36 ± 0.02c)

28.3 ± 0.9

0.124 ± 0.005c)

0.071 ± 0.002

5.1 ± 0.1c)

OVX

0.26 ± 0.02

31.6 ± 1.6

0.190 ± 0.010

0.064 ± 0.003

4.0 ± 0.1

ALF-L

0.27 ± 0.01**##

29.3 ± 0.4*##

0.183 ± 0.005**##

0.068 ± 0.001*##

4.0 ± 0.1**##

ALF-H

0.32 ± 0.01b)

26.7 ± 0.6a)

0.158 ± 0.004a)

0.088 ± 0.002b)

4.3 ± 0.1a)

RIS-L

0.27 ± 0.01*

29.3 ± 0.6*

0.181 ± 0.010

0.068 ± 0.001*

4.0 ± 0.1*

RIS-H

0.29 ± 0.01

28.4 ± 0.5

0.167 ± 0.005

0.071 ± 0.001

4.2 ± 0.1

ALF-L+RIS-L

0.31 ± 0.01a)

27.9 ± 0.3a)

0.157 ± 0.004a)

0.072 ± 0.001a)

4.4 ± 0.1a)

  1. BV/TV: bone volume, BS/BV: bone surface, Tb.Sp: trabecular separation, Tb.Th: trabecular thickness, Tb.N: trabecular number
  2. Mean ± SE (n = 7–8)
  3. a)p < 0.05, b)p < 0.01, c)p < 0.001 vs. OVX control group
  4. *p < 0.05, **p < 0.01 vs. ALF-L+RIS-L group
  5. #p < 0.05, ##p < 0.01 vs. ALF-H group