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Table 2 The effects of ALF and RIS on biomechanical properties of bones and urinary DPD excretion

From: The combination therapy with alfacalcidol and risedronate improves the mechanical property in lumbar spine by affecting the material properties in an ovariectomized rat model of osteoporosis

Variable

a two-way ANOVA1)

interaction

ALF-L

RIS-L

ALF × RIS

Urinary DPD excretion

<0.0001

0.0035

0.2115

L5 ultimate load (N)

0.0001

0.3290

0.1776

L5 stiffness (N/mm)

0.0345

0.1031

0.5763

L5 energy (mJ)

0.9173

0.6353

0.3556

Femur ultimate load (N)

0.0979

<0.0001

0.1821

Femur stiffness (N/mm)

0.5386

0.4792

0.6799

Femur energy (mJ)

0.1358

0.0009

0.6119

  1. 1) P values were obtained from a two-way ANOVA model.