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Table 1 Body weight and biochemical parameters

From: The combination therapy with alfacalcidol and risedronate improves the mechanical property in lumbar spine by affecting the material properties in an ovariectomized rat model of osteoporosis

Group

n

Body weight (g)

Serum Ca (mg/dL)

Serum P (mg/dL)

Urine Ca/CRE

Urine P/CRE

Sham

7

388 ± 14*

9.8 ± 0.2

6.1 ± 0.4

0.095 ± 0.038

1.66 ± 0.29

OVX

8

436 ± 13

10.4 ± 0.3

6.7 ± 0.8

0.144 ± 0.072

1.40 ± 0.13

ALF-L

8

469 ± 11

10.6 ± 0.1

6.7 ± 0.4

0.207 ± 0.031a)###

1.73 ± 0.25#

ALF-H

8

447 ± 13

10.1 ± 0.4

6.5 ± 0.2*

0.427 ± 0.040b)**

2.02 ± 0.21*

RIS-L

8

468 ± 10

9.9 ± 0.3a)

5.4 ± 0.2

0.027 ± 0.004b)

1.26 ± 0.11

RIS-H

8

459 ± 11

10.2 ± 0.1b)

5.4 ± 0.1a)

0.027 ± 0.004b)

1.31 ± 0.11

ALF-L + RIS-L

8

465 ± 15

10.7 ± 0.1

5.8 ± 0.1

0.132 ± 0.015##

1.56 ± 0.14

  1. Ca: calcium, P: inorganic phosphate, CRE: creatinine
  2. Mean ± SE (n = 7–8)
  3. *p < 0.05, **p < 0.01 vs. OVX control group
  4. a)p < 0.05, b)p < 0.001 vs. ALF-L+RIS-L group
  5. #p < 0.01, ##p < 0.01, ###p < 0.001 vs. ALF-H group