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Table 2 Cumulative lumbar load and lumbar disc disease among men

From: Cumulative occupational lumbar load and lumbar disc disease – results of a German multi-center case-control study (EPILIFT)

 

Control subjects

Lumbar disc herniation

Lumbar disc narrowing

 

N

%

N

%

Adj. ORa

95% CI

Adj. ORb

95% CI

N

%

Adj. ORa

95% CI

Adj. ORc

95% CI

Cumulative lumbar load through manual materials handling and/or intensive-load postures

   0 – <5.0*106Nh

159

35.1

54

18.9

1.0

-

1.0

-

27

18.6

1.0

-

  

   5.0 – <21.51*106Nh

147

32.5

76

26.6

1.6

1.0–2.4

1.7

1.1–2.7

31

21.4

1.6

0.9–2.8

  

   >21.51*106Nh

147

32.5

156

54.5

3.2

2.1–4.7

3.4

2.2–5.0

87

60.0

3.2

1.9–5.5

  

Cumulative lumbar load through manual materials handling

   0 – <2.34*106Nh

163

36.0

58

20.3

1.0

-

1.0

-

27

18.6

1.0

-

1.0

-

   2.34 – <8.98*106Nh

145

32.0

77

26.9

1.5

1.0–2.2

1.2

0.7–2.0

39

26.9

1.6

0.9–2.8

1.3

0.7–2.6

   > = 8.98*106Nh

145

32.0

151

52.8

2.8

1.9–4.1

2.0

1.2–3.5

79

54.5

2.9

1.7–4.9

2.4

1.2–4.6

Cumulative lumbar load through intensive-load postures

   0 Nh

129

28.5

45

15.7

1.0

-

1.0

-

26

17.9

1.0

-

1.0

-

   >0 – <4.85*106Nh

108

23.8

45

15.7

1.3

0.8–2.1

1.1

0.6–2.0

25

17.2

1.6

0.9–3.1

1.3

0.6–2.6

   4.85 – 14.62 *106Nh

108

23.8

84

29.4

2.3

1.4–3.6

1.7

0.9–3.2

37

25.5

2.0

1.1–3.6

1.4

0.7–2.9

   > = 14.62*106Nh

108

23.8

112

39.2

2.9

1.9–4.6

1.9

1.0–3.5

57

39.3

2.5

1.4–4.4

1.4

0.7–2.9

Lag-time analysis I: Cumulative lumbar load up to 10 years prior to diagnosis or interview date (in controls) = exposure during last 10 years set to zero

   0 – <5.0*106Nh

210

46.4

69

24.1

1.0

-

1.0

-

34

23.4

1.0

-

  

   5.0 – <21.51*106Nh

133

29.4

102

35.7

2.3

1.5–3.4

2.5

1.7–3.7

39

26.9

1.9

1.1–3.2

  

   > = 21.51*106Nh

110

24.3

115

40.2

3.5

2.3–5.4

3.7

2.4–5.7

72

49.7

3.1

1.8–5.3

  

Lag-time analysis II: Cumulative lumbar load; solely subjects unexposed in the last 10 years prior to diagnosis or interview date (in controls) = subjects exposed in the last 10 years excluded

   0 – <5.0*106Nh

37

36.6

15

23.8

1.0

-

1.0

-

9

22.0

1.0

-

  

   5.0 – <21.51*106Nh

38

37.6

28

44.4

1.7

0.8–3.9

2.0

0.9–4.7

11

26.8

1.5

0.5–4.5

  

   > = 21.51*106Nh

26

25.7

20

31.7

1.8

0.7–4.5

2.1

0.8–5.5

21

51.2

2.8

0.9–8.8

  
  1. a Adjusted for age and region
  2. b Adjusted for age, region, and unemployment as severe life event; OR for manual materials handling additionally adjusted for intensive-load postures and vice versa
  3. c Adjusted for age and region; OR for manual materials handling additionally adjusted for intensive-load postures and vice versa