Control subjects | Lumbar disc herniation | Lumbar disc narrowing | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | % | N | % | Adj. ORa | 95% CI | Adj. ORb | 95% CI | N | % | Adj. ORa | 95% CI | Adj. ORc | 95% CI | |
Cumulative lumbar load through manual materials handling and/or intensive-load postures | ||||||||||||||
0 – <5.0*106Nh | 159 | 35.1 | 54 | 18.9 | 1.0 | - | 1.0 | - | 27 | 18.6 | 1.0 | - | ||
5.0 – <21.51*106Nh | 147 | 32.5 | 76 | 26.6 | 1.6 | 1.0–2.4 | 1.7 | 1.1–2.7 | 31 | 21.4 | 1.6 | 0.9–2.8 | ||
>21.51*106Nh | 147 | 32.5 | 156 | 54.5 | 3.2 | 2.1–4.7 | 3.4 | 2.2–5.0 | 87 | 60.0 | 3.2 | 1.9–5.5 | ||
Cumulative lumbar load through manual materials handling | ||||||||||||||
0 – <2.34*106Nh | 163 | 36.0 | 58 | 20.3 | 1.0 | - | 1.0 | - | 27 | 18.6 | 1.0 | - | 1.0 | - |
2.34 – <8.98*106Nh | 145 | 32.0 | 77 | 26.9 | 1.5 | 1.0–2.2 | 1.2 | 0.7–2.0 | 39 | 26.9 | 1.6 | 0.9–2.8 | 1.3 | 0.7–2.6 |
> = 8.98*106Nh | 145 | 32.0 | 151 | 52.8 | 2.8 | 1.9–4.1 | 2.0 | 1.2–3.5 | 79 | 54.5 | 2.9 | 1.7–4.9 | 2.4 | 1.2–4.6 |
Cumulative lumbar load through intensive-load postures | ||||||||||||||
0 Nh | 129 | 28.5 | 45 | 15.7 | 1.0 | - | 1.0 | - | 26 | 17.9 | 1.0 | - | 1.0 | - |
>0 – <4.85*106Nh | 108 | 23.8 | 45 | 15.7 | 1.3 | 0.8–2.1 | 1.1 | 0.6–2.0 | 25 | 17.2 | 1.6 | 0.9–3.1 | 1.3 | 0.6–2.6 |
4.85 – 14.62 *106Nh | 108 | 23.8 | 84 | 29.4 | 2.3 | 1.4–3.6 | 1.7 | 0.9–3.2 | 37 | 25.5 | 2.0 | 1.1–3.6 | 1.4 | 0.7–2.9 |
> = 14.62*106Nh | 108 | 23.8 | 112 | 39.2 | 2.9 | 1.9–4.6 | 1.9 | 1.0–3.5 | 57 | 39.3 | 2.5 | 1.4–4.4 | 1.4 | 0.7–2.9 |
Lag-time analysis I: Cumulative lumbar load up to 10 years prior to diagnosis or interview date (in controls) = exposure during last 10 years set to zero | ||||||||||||||
0 – <5.0*106Nh | 210 | 46.4 | 69 | 24.1 | 1.0 | - | 1.0 | - | 34 | 23.4 | 1.0 | - | ||
5.0 – <21.51*106Nh | 133 | 29.4 | 102 | 35.7 | 2.3 | 1.5–3.4 | 2.5 | 1.7–3.7 | 39 | 26.9 | 1.9 | 1.1–3.2 | ||
> = 21.51*106Nh | 110 | 24.3 | 115 | 40.2 | 3.5 | 2.3–5.4 | 3.7 | 2.4–5.7 | 72 | 49.7 | 3.1 | 1.8–5.3 | ||
Lag-time analysis II: Cumulative lumbar load; solely subjects unexposed in the last 10 years prior to diagnosis or interview date (in controls) = subjects exposed in the last 10 years excluded | ||||||||||||||
0 – <5.0*106Nh | 37 | 36.6 | 15 | 23.8 | 1.0 | - | 1.0 | - | 9 | 22.0 | 1.0 | - | ||
5.0 – <21.51*106Nh | 38 | 37.6 | 28 | 44.4 | 1.7 | 0.8–3.9 | 2.0 | 0.9–4.7 | 11 | 26.8 | 1.5 | 0.5–4.5 | ||
> = 21.51*106Nh | 26 | 25.7 | 20 | 31.7 | 1.8 | 0.7–4.5 | 2.1 | 0.8–5.5 | 21 | 51.2 | 2.8 | 0.9–8.8 |