Figure 2From: Disease modifying and antiangiogenic activity of 2-Methoxyestradiol in a murine model of rheumatoid arthritis Abrogation of the Articular Inflammatory Response in Mice Treated with 2ME2. On study day 8, right and left hind paws were fixed in formalin, sectioned and stained by H&E. Intense inflammation is evident in the joints of mice receiving treatment with control diluent (A). In contrast, treatment of mice with 100 mg/kg/day of 2ME2 has essentially abrogated the inflammatory response (B). Magnification = 10×.Back to article page