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Table 1 Cut points for activity states according to various indexes (Panel A) and components of response criteria (Panel B)

From: Disease activity level, remission and response in established rheumatoid arthritis: Performance of various criteria sets in an observational cohort, treated with anti-TNF agents

A. Activity index

 

High

Moderate

Low

Remission

    

DAS28 original#

> 5,1

< 5,1

< 3,2

< 2,6

    

DAS28 modified cut off #

> 5,5

< 5,5

< 3,6

< 2,4

    

SDAI##

> 26

< 26

< 11

< 3,3

    

CDAI###

> 22

< 22

< 10

< 2,8

    

B. Response criteria

 

TJC

SJC

Patient global VAS

Patient pain VAS

Evaluator global

HAQ

ESR

CRP

ACR

yes

yes

yes/no

yes/no

yes/no

yes/no

yes/no

yes/no

EULAR

yes

yes

yes

no

no

no

yes

no

SDAI

yes

yes

yes

no

yes

no

no

yes

CDAI

yes

yes

yes

no

yes

no

no

no

  1. # DAS28 = 0,56x√TJC28+0,28x√SJC28x0,7xlnESR+0,014xPat global VAS(in mm)
  2. ## SDAI=SJC+TJC+Pat global VAS(in cm)+Eval global VAS(in cm)+CRP(in mg/dL)
  3. ### CDAI = SJC+TJC+Pat global VAS(in cm)+Eval global VAS(in cm)
  4. Cut points for activity states according to various indexes (Panel A) and components of response criteria (Panel B). Yes, required; no, not required; yes/no, in the ACR criteria, 3 of the variables marked "yes/no" are required (0 or 1 laboratory measure). TJC, tender joint count; SJC, swollen joint count; VAS, visual analogue scale; HAQ, health assessment questionnaire.