Figure 9From: Point mutation of tyrosine 759 of the IL-6 family cytokine receptor, gp130, augments collagen-induced arthritis in DBA/1J mice Methotrexate attenuated the increase of COMP levels (a) and anti-collagen antibody levels (b) in the serum on day 42. Values are expressed as mean ± standard error of 11 to 12 animals. *P < 0.05, **P < 0.01 versus vehicle-treated group by Student's t-test. aa P < 0.01 versus Non-immunized group (NI) by Student's t-test.Back to article page