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Table 4 Skeletal measures of participants stratified by age in the FORMEN baseline study, 2007-2008

From: Design and baseline characteristics of a prospective cohort study for determinants of osteoporotic fracture in community-dwelling elderly Japanese men: the Fujiwara-kyo Osteoporosis Risk in Men (FORMEN) Study

Index

All age groups

65-69 years

70-74 years

75-79 years

80 years and older

P for trend

BMD (g/cm2 )

LS

1.026 ± 0.191

1.022 ± 0.177

1.023 ± 0.185

1.030 ± 0.199

1.042 ± 0.226

0.1877

TH

0.878 ± 0.126

0.901 ± 0.124

0.880 ± 0.121

0.864 ± 0.129

0.841 ± 0.130

<0.0001

FN

0.740 ± 0.116

0.763 ± 0.117

0.741 ± 0.111

0.720 ± 0.114

0.715 ± 0.118

<0.0001

TR

0.684 ± 0.112

0.702 ± 0.109

0.685 ± 0.107

0.674 ± 0.117

0.651 ± 0.119

<0.0001

BMC (g)

LS

54.3 ± 13.3

54.2 ± 12.1

54.2 ± 13.4

54.5 ± 14.1

54.4 ± 14.4

0.7020

TH

36.5 ± 6.1

37.4 ± 6.3

36.5 ± 5.8

36.0 ± 5.9

35.2 ± 6.3

<0.0001

FN

3.9 ± 0.6

4.0 ± 0.6

3.9 ± 0.6

3.8 ± 0.6

3.8 ± 0.7

<0.0001

TR

8.9 ± 2.5

9.2 ± 3.5

8.9 ± 1.8

8.8 ± 1.8

8.5 ± 2.0

<0.0001

Area (cm2 )

LS

51.9 ± 5

52.2 ± 4.6

51.8 ± 5.1

52.0 ± 5.1

50.9 ± 5.2

0.0039

TH

41.6 ± 3.5

41.5 ± 3.6

41.5 ± 3.4

41.7 ± 3.3

41.8 ± 3.6

0.1959

FN

5.3 ± 0.4

5.2 ± 0.3

5.3 ± 0.4

5.3 ± 0.3

5.3 ± 0.3

0.0801

TR

13.0 ± 2.0

13.1 ± 2.7

13.0 ± 1.5

13.0 ± 1.5

13.1 ± 1.6

0.6968

Biochemical marker of bone turnover

OC (ng/ml)

4.8 (3.2, 6.5)

4.5 (2.6, 6.1)

4.8 (3.2, 6.5)

5.0 (3.5, 6.8)

5.4 (4.0, 6.9)

<0.0001

ucOC (ng/ml)

2.9 (1.5, 5.4)

2.7 (1.5, 4.9)

2.9 (1.6, 5.4)

3.0 (1.6, 5.7)

3.4 (1.8, 6.4)

<0.0001

TRACP-5b (mU/dl)

212.3 (121.7, 370.4)

200.2 (115.0, 348.7)

211.0 (120.2, 370.5)

212.3 (122.0, 369.3)

254.0 (152.5, 423.3)

<0.0001

  1. BMD: Bone mineral density
  2. BMC: Bone mineral content
  3. LS: Lumbar spine TH: Total hip FN: Femoral neck TR: Trochanter
  4. OC: Osteocalcin
  5. ucOC: Undercarboxylated osteocalcin
  6. TRACP-5b: Tartrate resistant acid phosphatase isoenzyme 5b
  7. Values of bone densitometric measures represent mean ± SD.
  8. OC values represent median with interquartile limits in parentheses.
  9. ucOC and TRACP-5b values represent geometric mean with values for M-SD and M+SD in parentheses.
  10. Bone densitometric data at the spine and at the hip were obtained from 1916 and 2008 participants, respectively, without severe deformities in the region of interest.
  11. Number of participants with available measurements for OC, ucOC and TRACP-5b were 1971, 1970 and 2003, respectively.