Table 2 Cognitive deficit in Fibromyalgia patients compared with subjects with neuropathic pain or mixed pain. Comparisons are overall, by level of symptoms of anxiety and depression, and by severity of present pain.
FMS (n = 46) | NeP (n = 92) | MP (n = 92) | P | |
|---|---|---|---|---|
MMSE scoring (Range 0-30); mean (95% CI) | 26.9 (26.7-27.1) | 27.3 (27.2-27.4) | 27.3 (27.2-27.5) | 0.001 (F = 7.32; df = 229) |
% patients with cognitive deficit (MMSE < 26); n, (%) [95% CI] | 7 (15%) [6.3-29] | 5 (5%) [1.8-12.2] | 5 (5%) [1.8-12.2] | 0.076 (X2 = 5.146; df = 2) |
% patients with cognitive deficit by Presence of symptoms of | ||||
Anxiety (COVI ≥ 9) | 7/14 (50%) [23-77] | 5/17 (29%) [10.3-56] | 5/15 (33%) [11.8-61.6] | 0.467 (X2 = 1.522; df = 2) |
Depression (RASKIN ≥ 9) | 7/19 (37%) [16.3-61.6] | 5/20 (25%) [8.6-49.1] | 5/21 (24%) [8.2-47.2] | 0.607 (X2 = 0.999; df = 2) |
Intensity of pain (average last week) | ||||
Mild (< 40) | 1/2 (50%) [12.6-98.7] | 1/7 (14%) [0.4-57.9] | 0-3 (0%) [0-70.8] | 0.328 (X2 = 2.229; df = 2) |
Moderate (≥40<70) | 2/15 (13%) [1.6-40.5] | 2/26 (8%) [0.9-25.1] | 1/26 (4%) [0-19.6] | 0.537 (X2 = 1.243; df = 2) |
Severe (≥ 70) | 4/29 (14%) [3.9-31.7] | 2/59 (3%) [0.4-11.7] | 4/63 (6%) [1.8-15.5] | 0.177 (X2 = 3.464; df = 2) |