|
Cartilage
|
Two step process for each joint surface:
|
Cartilage signal summarized as:
|
| |
1. Grade degree of cartilage damage:
|
0-None = normal
|
| |
0 = Normal
|
1-Mild = heterogeneity or fraying
|
| |
1 = Increased signal heterogeneity without surface disruption
|
2-Moderate = fissuring or thinning < 50%
|
| |
2 = Fraying (superficial only)
|
3-Severe = thinning > 50% or full thickness
|
| |
3 = Fissuring (full thickness lesions <1 mm in width)
|
Lesion size summarized as:
|
| |
4 = Thinning <50% cartilage thickness
|
0-None = normal
|
| |
5 = Thinning >50% cartilage thickness
|
1-Mild = < 1 cm
|
| |
6 = Full thickness cartilage loss
|
2-Moderate = 1-2 cm
|
| |
2. Score greatest diameter of greatest severity lesion
|
3-Severe = > 2 cm
|
| |
0 = Normal
|
Cartilage signal and lesion size scores summed over 17 regions to give hypothetical range 0-102.
|
| |
1 = <1 cm
|
None = 0
|
| |
2 = 1-2 cm
|
Mild = 1-30
|
| |
3 = 2-3 cm
|
Moderate = 30-60
|
| |
4 = >3 cm
|
Severe = > 60
|
|
Osteophytes
|
Two step process for each joint compartment:
|
Compartmental scores (medial, lateral, patellofemoral) were summed for the whole knee. The possible score range was 0-9. Final assessment of osteophytosis:
|
| |
1. Grade individual osteophytes according to the size of the greatest dimension:
|
None = 0
|
| |
0 = <1 mm
|
Mild = 1-3
|
| |
1 = 1-2 mm
|
Moderate = 4-5
|
| |
2 = 2-5 mm
|
Severe = 6+
|
| |
3 = >5 mm
| |
| |
2. Sum scores of all individual osteophytes to give compartmental score:
| |
| |
0 = normal individual sum 0
| |
| |
1 = mild individual sum 1-2
| |
| |
2 = moderate individual sum 3-4
| |
| |
3 = severe individual sum >4
| |
|
Bone Marrow Lesions
|
Greatest diameter of each lesion recorded for both femoral and tibial surfaces as well as the patellofemoral compartment:
|
Scores for patellofemoral compartment and femoral and tibial surfaces were summed. The possible score range was 0-15. Final assessment of bone marrow lesions:
|
| |
0 = None
|
None = 0
|
| |
1 = Mild (<0.5 cm)
|
Mild = 1-3
|
| |
2 = Moderate (0.5-1.5 cm)
|
Moderate = 4-5
|
| |
3 = Severe (>1.5 cm)
|
Severe = 6+
|
|
Effusion
|
Greatest diameter of the effusion perpendicular to the long-axis of the leg:
|
Effusion was recorded as a single score for the whole knee. No changes were made for final analysis.
|
| |
0 = None (0.0-0.5 cm fluid)
| |
| |
1 = Mild (0.5 -- 1.0 cm fluid)
| |
| |
2 = Moderate (1.0 -- 2.0 cm fluid)
| |
| |
3 = Severe (>2.0 cm fluid)
| |
|
Synovitis
|
Assessed by counting the number of thickened villi seen on T2-weighted sequences
|
Synovitis was recorded as a single score for the whole knee. No changes were made for final analysis.
|
| |
0 = None (<5 villi seen, all normal thickness)
| |
| |
1 = Mild (6-10 villi seen, some thickened)
| |
| |
2 = Moderate (11-15 villi seen, mostly thickened)
| |
| |
3 = Severe (> 15 villi seen, marked thickening)
| |
|
Subchondral Sclerosis
|
For each compartment:
|
Final score determined by number of the 3 knee compartments with evidence of sclerotic change
|
| |
0 = Absent
|
0 = Absent
|
| |
1 = Present
|
1 = Mild
|
| | |
2 = Moderate
|
| | |
3 = Severe
|
