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  1. Research article

    Implementing the Keele stratified care model for patients with low back pain: an observational impact study

    The Keele stratified care model for management of low back pain comprises use of the prognostic STarT Back Screening Tool to allocate patients into one of three risk-defined categories leading to associated ri...

    Adrian Bamford, Andy Nation, Susie Durrell, Lazaros Andronis, Ellen Rule and Hugh McLeod

    BMC Musculoskeletal Disorders 2017 18:66

    Published on: 3 February 2017

  2. Research article

    Correlation of blood bone turnover biomarkers and Wnt signaling antagonists with AS, DISH, OPLL, and OYL

    Wnt signaling plays an important role in development and maintenance of many organs and tissues. The most-studied secreted Wnt inhibitors are sclerostin (SOST), Dickkopf-related protein 1 (DKK-1), and secreted...

    Chi-Chien Niu, Song-Shu Lin, Li-Jen Yuan, Lih-Huei Chen, Chuen-Yung Yang, An-Ni Chung, Meng-Ling Lu, Tsung-Ting Tsai, Po-Liang Lai and Wen-Jer Chen

    BMC Musculoskeletal Disorders 2017 18:61

    Published on: 2 February 2017

  3. Research article

    Biomechanical comparison of multilevel lateral interbody fusion with and without supplementary instrumentation: a three-dimensional finite element study

    Lateral lumbar interbody fusion (LLIF) is a popular, minimally invasive technique that is used to address challenging multilevel degenerative spinal diseases. It remains controversial whether supplemental inst...

    Xilin Liu, Jun Ma, Paul Park, Xiaodong Huang, Ning Xie and Xiaojian Ye

    BMC Musculoskeletal Disorders 2017 18:63

    Published on: 2 February 2017

  4. Research article

    Intramedullary cortical bone strut improves the cyclic stability of osteoporotic proximal humeral fractures

    Proximal humeral fractures treated with locking plate can fail due to varus collapse, especially in osteoporotic bone with medial cortex comminution. The use of an intramedullary strut together with locking pl...

    Chih-Kun Hsiao, Yi-Jung Tsai, Cheng-Yo Yen, Cheng-Hung Lee, Teng-Yao Yang and Yuan-Kun Tu

    BMC Musculoskeletal Disorders 2017 18:64

    Published on: 2 February 2017

  5. Case report

    Restoration of a large osteochondral defect of the knee using a composite of umbilical cord blood-derived mesenchymal stem cells and hyaluronic acid hydrogel: a case report with a 5-year follow-up

    The treatment of articular cartilage defects is a therapeutic challenge for orthopaedic surgeons. Furthermore, large osteochondral defects needs restoration of the underlying bone for sufficient biomechanical ...

    Yong-Beom Park, Chul-Won Ha, Choong-Hee Lee and Yong-Geun Park

    BMC Musculoskeletal Disorders 2017 18:59

    Published on: 2 February 2017

  6. Research article

    Musculoskeletal disorders as underlying cause of death in 58 countries, 1986–2011: trend analysis of WHO mortality database

    Due to low mortality rate of musculoskeletal disorders (MSK) less attention has been paid to MSK as underlying cause of death in the general population. The aim was to examine trend in MSK as underlying cause ...

    Aliasghar A. Kiadaliri, Anthony D. Woolf and Martin Englund

    BMC Musculoskeletal Disorders 2017 18:62

    Published on: 2 February 2017

  7. Research article

    Agonist muscle adaptation accompanied by antagonist muscle atrophy in the hindlimb of mice following stretch-shortening contraction training

    The vast majority of dynamometer-based animal models for investigation of the response to chronic muscle contraction exposure has been limited to analysis of isometric, lengthening, or shortening contractions ...

    Erik P. Rader, Marshall A. Naimo, James Ensey and Brent A. Baker

    BMC Musculoskeletal Disorders 2017 18:60

    Published on: 2 February 2017

  8. Study protocol

    Efficacy of paracetamol, diclofenac and advice for acute low back pain in general practice: design of a randomized controlled trial (PACE Plus)

    Low back pain is common and associated with a considerable burden to patients and society. There is uncertainty regarding the relative benefit of paracetamol and diclofenac and regarding the additional effect ...

    M. Schreijenberg, P. A. J. Luijsterburg, Y. D. M. Van Trier, D. Rizopoulos, M. A. Koopmanschap, L. Voogt, C. G. Maher and B. W. Koes

    BMC Musculoskeletal Disorders 2017 18:56

    Published on: 1 February 2017

  9. Technical advance

    Identifying subgroups of patients using latent class analysis: should we use a single-stage or a two-stage approach? A methodological study using a cohort of patients with low back pain

    Heterogeneity in patients with low back pain (LBP) is well recognised and different approaches to subgrouping have been proposed. Latent Class Analysis (LCA) is a statistical technique that is increasingly bei...

    Anne Molgaard Nielsen, Peter Kent, Lise Hestbaek, Werner Vach and Alice Kongsted

    BMC Musculoskeletal Disorders 2017 18:57

    Published on: 1 February 2017

  10. Research article

    Utilization of CT scanning associated with complex spine surgery

    Due to the risk associated with exposure to ionizing radiation, there is an urgent need to identify areas of CT scanning overutilization. While increased use of diagnostic spinal imaging has been documented, n...

    Vikas V. Patel, Gunnar B. J. Andersson, Steven R. Garfin, Donald L. Resnick and Jon E. Block

    BMC Musculoskeletal Disorders 2017 18:52

    Published on: 31 January 2017

  11. Research article

    Multiplanar evaluation of radiological findings associated with acetabular dysplasia and investigation of its prevalence in an Asian population: a CT-based study

    Acetabular dysplasia (AD) is a well-known cause of osteoarthritis (OA) of the hip, with its prevalence previously determined on plain radiography. The prevalence of preexisting AD was reported as 7.3% in a pat...

    Tomohiro Mimura, Kanji Mori, Masahiro Kitagawa, Mariko Ueki, Yuki Furuya, Taku Kawasaki and Shinji Imai

    BMC Musculoskeletal Disorders 2017 18:50

    Published on: 31 January 2017

  12. Technical advance

    Modified minimally invasive extensor carpi radialis longus tenodesis for scapholunate dissociation: a prospective observational study

    Scapholunate dissociation is the most common form of carpal instability. However, there is no gold standard for operative treatment. In this prospective observational study on 54 patients, a modified minimally...

    Alexander Kaltenborn, Sebastian Hoffmann, Andreas Settje, Peter M. Vogt, André Gutcke and Mike Rüttermann

    BMC Musculoskeletal Disorders 2017 18:54

    Published on: 31 January 2017

  13. Research article

    Intertester and intratester reliability of movement control tests on the hip for patients with hip osteoarthritis

    Hip joint complaints are a problem associated with increasing age and impair the mobility of a large section of the elderly population. Reliable and valid tests are necessary for a thorough investigation of a ...

    Rahel Lenzlinger-Asprion, Niculina Keller, André Meichtry and Hannu Luomajoki

    BMC Musculoskeletal Disorders 2017 18:55

    Published on: 31 January 2017

  14. Study protocol

    Individualized patient decision-aid for immunosuppressive drugs in women with lupus nephritis: study protocol of a randomized, controlled trial

    Systemic Lupus erythematosus (SLE), also commonly referred to as lupus, is a rare, but sometimes, fatal disease, that primarily affects young women. Lupus nephritis, a common manifestation of lupus, is more co...

    Jasvinder A. Singh, Nipam Shah and Candace Green

    BMC Musculoskeletal Disorders 2017 18:53

    Published on: 31 January 2017

  15. Technical advance

    Direct anterior approach for total hip arthroplasty with a novel mobile traction table -a prospective cohort study

    The purpose of this prospective cohort study was to clarify the safety and efficacy of total hip arthroplasty via the direct anterior approach in the supine position with a novel mobile traction table.

    Junichi Nakamura, Shigeo Hagiwara, Sumihisa Orita, Ryuichiro Akagi, Takane Suzuki, Masahiko Suzuki, Kazuhisa Takahashi and Seiji Ohtori

    BMC Musculoskeletal Disorders 2017 18:49

    Published on: 31 January 2017

  16. Research article

    Consensus on draft OMERACT core domains for clinical trials of Total Joint Replacement outcome by orthopaedic surgeons: a report from the International consensus on outcome measures in TJR trials (I-COMiTT) group

    There are no core outcome domain or measurement sets for Total Joint Replacement (TJR) clinical trials. Our objective was to achieve an International consensus by orthopaedic surgeons on the OMERACT core domai...

    Jasvinder A. Singh, Michael Dohm and Peter F. Choong

    BMC Musculoskeletal Disorders 2017 18:45

    Published on: 26 January 2017

  17. Review

    An overview of osteoporosis and frailty in the elderly

    Osteoporosis and osteoporotic fractures remain significant public health challenges worldwide. Recently the concept of frailty in relation to osteoporosis in the elderly has been increasingly accepted, with em...

    Guowei Li, Lehana Thabane, Alexandra Papaioannou, George Ioannidis, Mitchell A. H. Levine and Jonathan D. Adachi

    BMC Musculoskeletal Disorders 2017 18:46

    Published on: 26 January 2017

  18. Research article

    Magnetic resonance imaging evaluation of the distal oblique bundle in the distal interosseous membrane of the forearm

    Some cadaveric studies have reported the role of the distal oblique bundle (DOB) in the distal radioulnar joint stability. We aimed to determine whether the presence of the DOB can be identified and its thickn...

    Yeon Ho Kim, Hyun Sik Gong, Jin Woo Park, Hyun Kyung Yang, Kahyun Kim and Goo Hyun Baek

    BMC Musculoskeletal Disorders 2017 18:47

    Published on: 26 January 2017

  19. Research article

    Accuracy of injection and short-term pain relief following intra-articular corticosteroid injection in knee osteoarthritis – an observational study

    Intra-articular corticosteroid injections (IACI) are effective treatments for pain in knee osteoarthritis (KOA) but treatment response varies. There is uncertainty as to whether structural factors such as accu...

    G. Hirsch, T. W. O’Neill, G. Kitas, A. Sinha and R. Klocke

    BMC Musculoskeletal Disorders 2017 18:44

    Published on: 26 January 2017

  20. Research article

    Strenuous running exacerbates knee cartilage erosion induced by low amount of mono-iodoacetate in rats

    It is still debated whether strenuous running in the inflammatory phase produces beneficial or harmful effect in rat knees. We examined (1) the dropout rate of rats during a 30-km running protocol, (2) influen...

    Ryusuke Saito, Takeshi Muneta, Nobutake Ozeki, Yusuke Nakagawa, Mio Udo, Katsuaki Yanagisawa, Kunikazu Tsuji, Makoto Tomita, Hideyuki Koga and Ichiro Sekiya

    BMC Musculoskeletal Disorders 2017 18:36

    Published on: 25 January 2017

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