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The PRICE study (Protection Rest Ice Compression Elevation): design of a randomised controlled trial comparing standard versus cryokinetic ice applications in the management of acute ankle sprain [ISRCTN13903946]

  • Chris M Bleakley1Email author,
  • Seán O'Connor1,
  • Mark A Tully1,
  • Laurence G Rocke2,
  • Domnhall C MacAuley3 and
  • Suzanne M McDonough1
BMC Musculoskeletal Disorders20078:125

DOI: 10.1186/1471-2474-8-125

Received: 04 October 2007

Accepted: 19 December 2007

Published: 19 December 2007

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
4 Oct 2007 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
Resubmission - Version 3
Submitted Manuscript version 3
13 Dec 2007 Author responded Author comments - Sean O'Connor
Resubmission - Version 4
13 Dec 2007 Submitted Manuscript version 4
19 Dec 2007 Editorially accepted
19 Dec 2007 Article published 10.1186/1471-2474-8-125

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

Health & Rehabilitation Sciences Research Institute, University of Ulster
Department of Emergency Medicine, Royal Victoria Hospital
Hillhead Family Practice