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Real-world effectiveness of abatacept for rheumatoid arthritis treatment in European and Canadian populations: a 6-month interim analysis of the 2-year, observational, prospective ACTION study

  • Hubert G Nüßlein1Email author,
  • Rieke Alten2,
  • Mauro Galeazzi3,
  • Hanns-Martin Lorenz4,
  • Dimitrios Boumpas5,
  • Michael T Nurmohamed6,
  • William G Bensen7,
  • Gerd R Burmester8,
  • Hans-Hartmut Peter9,
  • Franz Rainer10,
  • Karel Pavelka11,
  • Melanie Chartier12,
  • Coralie Poncet13,
  • Christiane Rauch14 and
  • Manuela Le Bars15
BMC Musculoskeletal Disorders201415:14

DOI: 10.1186/1471-2474-15-14

Received: 3 September 2013

Accepted: 2 January 2014

Published: 11 January 2014

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting

Original Submission
3 Sep 2013 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
30 Oct 2013 Reviewed Reviewer Report - László Hodinka
5 Nov 2013 Reviewed Reviewer Report - Alain Saraux
10 Dec 2013 Author responded Author comments - Hubert Nuesslein
Resubmission - Version 3
10 Dec 2013 Submitted Manuscript version 3
2 Jan 2014 Editorially accepted
11 Jan 2014 Article published 10.1186/1471-2474-15-14

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

University of Erlangen-Nuremberg
Schlosspark-Klinik, University Medicine
University of Siena
University Hospital Heidelberg
University of Crete
VU University Medical Center/Jan van Breemen Research Institute
St. Joseph’s Hospital/McMaster University
Charité-Universitätsmedizin Berlin
University Medical Center Freiburg
Hospital Barmherzige Brueder
Institute of Rheumatology and Clinic of Rheumatology, Charles University
Chiltern International
Docs International
Bristol-Myers Squibb
Bristol-Myers Squibb